Cardiac Health | Genetic Testing Services | Kashi Clinical Laboratories

Cardiac Health

Cardiac Health | Genetic Testing Services | Kashi Clinical Laboratories

The Kashi Cardiac Health Panel gives insight into how a patient’s genetic predisposition to cardiac problems can help healthcare providers optimize diagnosis and treatment.

Cardiovascular disease is a leading contributor to morbidity and mortality, with over 17 million deaths occurring annually worldwide. Risk increases in adults over the age of 60, and in part is attributable to inherited genetic makeup.

Cardiovascular disease – which includes coronary heart disease, cerebrovascular disease, peripheral artery disease, and atherosclerosis – is heavily influenced by factors such as insulin resistance, hypertension, dyslipidemia, inflammation, and coagulation properties. Many of these factors can be mitigated by lifestyle changes including smoking cessation, increasing aerobic exercise, and eating a well-balanced diet, which can reduce the risk of catastrophic events such as myocardial infarction, or ischemic and hemorrhagic stroke. However, in some cases, particularly where family history of cardiovascular disease is prevalent, medications or more targeted lifestyle interventions are needed to better manage health outcomes.

ApoE 4 does not guarantee that someone will develop Alzheimer’s. After learning about an individual’s genetic makeup, we can recommend steps to take to reduce your risk of developing the disease.

Genetic Markers

Test Categories
Health Effects

ApoE

Impacts management of cholesterol levels and risk of heart attack, stroke, hypertension, and coronary disease

Factor II (Prothrombin)

Affects the body’s ability to form blood clots which is tied to the risk of many cardiovascular-related health outcomes

Factor V

Enhances body’s coagulability which leads to thromboembolisms

MTHFR

Contributes to increased levels of homocysteine, a known risk factor for heart disease, atherosclerosis, and peripheral neuropathy

9p21

Associated with cellular growth and proliferation in relation to atherosclerosis, arterial stiffness and coronary artery disease

eNOS/NOS3

Influences nitric oxide levels leading to risk of endothelial dysfunction, and many subsequent cardiovascular effects

SLCO1B1*5

Modulates the body’s ability to metabolize statin medications, which are commonly prescribed to improve cholesterol

AGT

Key to maintaining blood pressure, patients who carry this mutation may be at an increased risk of developing hypertension

For Cardiac Pharmacogenetics, these SNPs are ordered as part of our PGx Comprehensive panel: CYP2D6, CYP2C19, CYP2C9, CYP3A4, CYP3A5, VKOPC1

Ideal candidates are patients with the following symptoms or conditions:

Treatment-resistant hypertension

Poor control over cholesterol levels

Personal history of angina, DVT, PE, CHF, MI or CVA

Introduction of new statin medications

Family history of cardiovascular disease

Stroke or heart disease in the young

Idiopathic cardiovascular disease

Environmental Testing | Kashi Clinical Laboratories

Kashi Laboratories works directly with providers to make ordering tests as easy as possible.

To request environmental testing at Kashi Labs, please visit the Order Now page and contact us to get started.

Kashi Laboratories works directly with providers to make ordering tests as easy as possible.

To request toxicology testing at Kashi Labs, please visit the Order Now page and contact us to get started.

What can we help you find?

Place a one-time order for genetic testing at order.kashilab.com.

If you are an existing provider, please sign in to place an order through the online portal. If you are new to Kashi and would like to create an account, please contact us.

Kashi Laboratories works directly with providers to make ordering tests as easy as possible.

Place a one-time order by contacting us through the form at the link below, or get started by logging in to your online portal.

Ordering a kit is easy! To purchase a Private Testing Kit, please visit the link below and follow the steps provided.

BoneMarrowTest.com is a service of Kashi Clinical Laboratories. For more information regarding Private HLA Testing or to order a test kit, please visit BoneMarrowTest.com.

*By clicking the link above you will be redirected to BoneMarrowTest.com.

Antibody Testing | HLA Antibody Testing | Kashi Clinical Laboratories

Kashi Labs has partnered with ThermoFisher to bring MMDx to our patients and providers.

Find more information regarding MMDx for Molecular Biopsy Assessment, sample reports, and free specimen collection kit orders.

*By clicking the link above you will be redirected to the ThermoFisher website.