August 17, 2018

Estrogen Clearance: Genetic Insights into Optimal Treatment Choices

Although it is known for its pivotal role in the female body, estrogen is a vital hormone for both men and women. On a molecular level estrogen’s effects are mediated by the estrogen receptor (ER), a dimeric nuclear protein that binds to DNA and controls gene expression. The functions of estrogen are wide ranging, from reducing bowel motility to controlling the type of melanin being produced in the skin.

August 2, 2018

Genetic Clues to a Happy, Health Brain

The health of the brain is dependent on numerous things; environment, lifestyle and genetics. Many people can see how they are likely to age by observing changes in their parents, and fears can often grow concerning the genetics of aging. Aside from rare genetic conditions like early onset Alzheimer’s Disease, there are several more common genetic polymorphisms that play an important role in brain health.

July 20, 2018

Graceful Aging

For many people, the term aging can conjure images of thinning hair, night sweats, and hip replacements. But aging is a beautiful, reliable part of life that can be managed effectively by determining our genetic tendencies coupled with healthful lifestyle choices.

July 5, 2018

M is for Methylation, how to use genetic clues

Methylation involves the transfer of a small molecule, similar in size to H2O, containing one carbon and four hydrogens. The availability and transfer of that little methyl molecule is an incredible contributor to many of the biochemical pathways integral to the function of human life. Methylation plays a significant role in regulating homocysteine levels, stabilizing epigenetics, potentially silencing oncogenes, supporting phase II liver detoxification, and modulating aging.

July 2, 2018

How do YOU choose the research?

For the integrative practitioner stepping into a more extended use of SNP testing, knowing which research to rely on is a key component for clinical success. Scientific research may be defined as “systematic, controlled, empirical, and critical investigation of hypothetical propositions about the presumed relations among observed phenomena.

June 6, 2018

Kashi Quick Quiz

Are you a DNA dynamo? A SNP superhero? Test your genetic knowledge in this week's Kashi Quick Quiz! Reply by June 15, 2018 with your answers to newsletter@kashi.

March 16, 2018

A Leptin Resistance Solution?

Leptin is a hormone that signals the very important message, “I am not hungry”.  In a culture that has easy access to tempting foods, why would anyone ever want to stop eating?  The answer to this question lies in the body’s ability to feel full.  Leptin is produced primarily by adipose tissue and, when the systems works the way it should, the body increases leptin levels which triggers a decrease in appetite1.

March 3, 2018

Coconut Oil the Super Food, Is it Right for Everyone?

Most people who think about healthy foods think about coconut oil.  With the surge of interest you can now find it in every store.  But the question most people should be asking is if it is right for everyone.  FABP2 is a gene that is involved in fat absorption through the digestive tract by encoding for a protein that is crucial for the effective binding of fatty acids2.

February 24, 2018

MC4R Gene – the Obesity Link

The escalating population prevalence of obesity and its serious implications for public health are now generally accepted. Throughout the last twenty years, the industrialized world has transitioned from low calorie density food to high calorie density food.  The ease of resource distribution, the invention of trans-fats which prolonged shelf life of food, the recent unlimited availability of low-cost calorie-dense food, along with increasing sedentary lifestyle, has played a major role in the adult obesity pandemic.

February 8, 2018

Goldilocks: “like porridge, leptin needs to be juuuuust right.”

Leptin is a hormone secreted primarily in white adipose fat cells and plays a role in regulating energy balance by curbing or stimulating hunger.  Often referred to as the "satiety hormone," leptin works by signaling the need to start or stop eating. In the short term, as fat supplies are reduced, leptin levels drop to signal when enough food has been consumed per meal.

January 24, 2018

The 9p21 Gene and Atherosclerosis Risk

Cardiovascular disease is a leading contributor to morbidity and mortality, with 17.3 million deaths annually worldwide. Partly genetically-inherited, it is a particular risk for adults over age 60. Cardiovascular disease – coronary heart disease, cerebrovascular disease, peripheral artery disease, and atherosclerosis -- are heavily influenced by factors such as insulin resistance, hypertension, dyslipidemia, inflammation, and coagulation properties.

January 4, 2018

Heart Health, Brain Health and Apolipoprotein E

The heart and the brain may seem separate at first glance, but doctors know everything is connected.  Heart and brain health are important to help patients to both survive, and thrive.  One of the key players in the health of these two systems is a protein by the name of Apolipoprotein E (ApoE).