The Kashi Bone Health Panel gives insight into how a patient absorbs the nutrients important for proper bone health, allowing for patients and healthcare providers to make informed dietary and supplement choices.Strong bones are critical to good health. While healthy bones are influenced by environmental elements such as nutrition, genetics also play a major role. Osteoporosis, characterized by low bone mass, is a major problem in older adults.
Today, about 30 to 50 % of American women and 15 to 30 %of American men will experience an osteoporosis-related fracture sometime in their lifetime. Studies have demonstrated that bone mineral density in older adults is influenced by genes underlying bone accrual and bone loss; in fact, up to 85 %of the variation in peak bone mineral density can be explained by genetic factors. However, only recently have these specific genes, and their variants, been identified.
Genetic Markers Included in the Bone Health Panel
|TEST CATEGORIES||EFFECTS ON BONE HEALTH|
|Vitamin D||Tests three genes that function in the Vitamin D metabolism pathway involved in transportation of vitamin D to target organs, conversion of the inactive form of vitamin D to the active form, and bioavailability of the vitamin D precursor|
|WNT16||Essential to proper protein signaling involved in the regulation of bone formation|
|Estrogen Receptor 1||Crucial to the process of bone resorption|
Ideal Candidates are Patients with the Following Symptoms or Conditions
- Diagnosed with osteoporosis or osteopenia
- Conditions that prevent proper vitamin D absorption
- Individuals with compromised mobility
- People in low sun exposure areas
- Menopausal changes
- History of a minimal-trauma fracture
- Low blood calcium (hypocalcemia)
- Low blood phosphate (hypophosphatemia)